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Another theory focuses on reduced vagal stimulation of the enteric system after brain trauma [40]

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However, certain changes, such as the transcriptional upregulation of SLC7A11 (which encodes the transport subunit of system x c − ) 58 , might be expected to reduce ferroptosis sensitivity, while changes in viscosity or pH could very well modulate the function of one or more ER-resident enzymes or mechanisms noted above